Lipopolysaccharide as a target for brucellosis vaccine design
نویسندگان
چکیده
منابع مشابه
Preparation and Evaluation of a New Lipopolysaccharide-based Conjugate as a Vaccine Candidate for Brucellosis
OBJECTIVES Development of an efficacious vaccine against brucellosis has been a challenge for scientists for many years. At present, there is no licensed vaccine against human brucellosis. To overcome this problem, currently, antigenic determinants of Brucella cell wall such as Lipopolysaccharide (LPS) are considered as potential candidates to develop subunit vaccines. METHODS In this study, ...
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Abstract Background and Objective: One of the proteins shared in all strains of Brucella is 31 kDa surface protein (BCPS31) that could be an appropriate target for immunization and serological diagnosis. Material and Methods: In the present study, BCSP31 produced as a recombinant protein in pET28a (+) expression system was utilized, using ELISA, to detect trace specific antibody (IgG) in brucel...
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ژورنال
عنوان ژورنال: Microbial Pathogenesis
سال: 2013
ISSN: 0882-4010
DOI: 10.1016/j.micpath.2012.11.011